Radiation Therapy For Keloids
The combination therapy of surgical excision and radiation therapy was deemed as the last resort for decades. Radiation treatment of keloid scars.
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Radiation is a controversial therapy because of potentially serious harmful side effects of ionizing radiation.
Radiation therapy for keloids. Radiation therapy was applied with a 6 mev electron beam. Compared to surgery or radiation therapy alone surgical excision followed by immediate postoperative radiation therapy has been shown to be the most effective treatment with a recurrence rate of about 20. Recurrence rate reduced to 50 with intralesional steroid therapy.
Keloid management has always been frustrating and challenging. No universally accepted treatment protocol. The authors performed a thorough and comprehensive review over the mechanisms on how radiation therapy damages the keloid cells.
Surgery radiation pressure therapy cryotherapy intralesional injections of corticosteroids interferon fluorouracil topical silicone and pulse dye laser. Coupled with the wide range of response to its use as a monotherapyfrom 10 94 simply makes it not worth the potential long term risks of cancer or stunted growth associated with radiation. Keloids have been treated by using radiation for over a century and it is currently suggested that keloids are best treated by a combination of surgery and postoperative radiation therapy although randomized controlled trials testing this are still lacking.
To ensure an adequate radiation dose was applied to the surface of the skin a 05 or 1 cm thick silicone bolus such as a tissue compensator was placed on the keloid surgical scar based on the characteristics of the scar. Radiation is often indicated for recurrent keloids or for patients with a high risk of recurrence including marginal resections wider. Rt reduces recurrence rate to 12 28.
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